PhD Program

2017

Journal Article

Chandrasekar, B.; Tram Hong, N.; Van der Hoorn, R. A. L.: Inhibitor Discovery by Convolution ABPP. ACTIVITY-BASED PROTEOMICS: METHODS AND PROTOCOLS, pp. 47 - 56 (2017)

MPG.PuRe

DOI

Journal Article

Kovacs, J.; Poor, P.; Kaschani, F.; Chandrasekar, B.; Hong, T. N.; Misas-Villamil, J. C.; Xin, B. T.; Kaiser, M.; Overkleeft, H. S.; Tari, I. et al.; Van der Hoorn, R. A. L.: Proteasome Activity Profiling Uncovers Alteration of Catalytic beta 2 and beta 5 Subunits of the Stress-Induced Proteasome during Salinity Stress in Tomato Roots. Frontiers in Plant Science 8, 107 (2017)

MPG.PuRe

DOI

publisher-version

Journal Article

Misas-Villamil, J.; van der Burgh, A. M.; Grosse-Holz, F.; Bach-Pages, M.; Kovács, J.; Kaschani, F.; Schilasky, S.; Emon, A. E. K.; Ruben, M.; Kaiser, M. et al.; Overkleeft, H. S.; Van der Hoorn, R. A. L.: Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections. The Plant Journal 90 (2), pp. 418 - 430 (2017)

MPG.PuRe

DOI

publisher-version

Journal Article

Poret, M.; Chandrasekar, B.; Van der Hoorn, R. A. L.; Coquet, L.; Jouenne, T.; Avice, J.-C.: Proteomic Investigations of Proteases Involved in Cotyledon Senescence: A Model to Explore the Genotypic Variability of Proteolysis Machinery Associated with Nitrogen Remobilization Efficiency during the Leaf Senescence of Oilseed Rape. PROTEOMES 5 (4), UNSP 29 (2017)

MPG.PuRe

DOI

Journal Article

Pruzinska, A.; Shindo, T.; Niessen, S.; Kaschani, F.; Tóth, R.; Millar, A. H.; Van der Hoorn, R. A. L.: Major Cys protease activities are not essential for senescence in individually darkened Arabidopsis leaves. BMC Plant Biology 17, 4 (2017)

MPG.PuRe

DOI

publisher-version

2016

Journal Article

Chandrasekar, B.; Van der Hoorn, R. A. L.: Beta galactosidases in Arabidopsis and tomato - a mini review. Biochemical Society Transactions (London) 44, pp. 150 - 158 (2016)

MPG.PuRe

DOI

publisher-version

Journal Article

Kaschani, F.; Wei, Q.; Dingemans, J.; Van der Hoorn, R. A. L.; Cornelis, P.; Kaiser, M.: Capture of endogenously biotinylated proteins from Pseudomonas aeruginosa displays unexpected downregulation of LiuD upon iron nutrition. Bioorganic & Medicinal Chemistry 24 (15), pp. 3330 - 3335 (2016)

MPG.PuRe

DOI

Journal Article

Poret, M.; Chandrasekar, B.; Van der Hoorn, R. A. L.; Avice, J.-C.: Characterization of senescence-associated protease activities involved in the efficient protein remobilization during leaf senescence of winter oilseed rape. Plant Science 246, pp. 139 - 153 (2016)

MPG.PuRe

DOI

publisher-version

Journal Article

Shindo, T.; Kaschani, F.; Yang, F.; Kovacs, J.; Tian, F.; Kourelis, J.; Hong, T. N.; Colby, T.; Shabab, M.; Chawla, R. et al.; Kumari, S.; Ilyas, M.; Hoerger, A. C.; Alfano, J. R.; Van der Hoorn, R. A. L.: Screen of Non-annotated Small Secreted Proteins of Pseudomonas syringae Reveals a Virulence Factor That Inhibits Tomato Immune Proteases. PLoS Pathogens 12 (9), e1005874 (2016)

MPG.PuRe

DOI

publisher-version

Journal Article

Stiti, N.; Chandrasekar, B.; Strubl, L.; Mohammed, S.; Bartels, D.; Van der Hoorn, R. A. L.: Nicotinamide Cofactors Suppress Active-Site Labeling of Aldehyde Dehydrogenases. ACS Chemical Biology 11 (6), pp. 1578 - 1586 (2016)

MPG.PuRe

2015

Journal Article

Huetten, M.; Geukes, M.; Misas-Villamil, J.; Van der Hoorn, R. A. L.; Grundler, F. M. W.; Siddique, S.: Activity profiling reveals changes in the diversity and activity of proteins in Arabidopsis roots in response to nematode infection. Plant Physiology and Biochemistry 97, pp. 36 - 43 (2015)

MPG.PuRe

DOI

Journal Article

Ilyas, M.; Hoerger, A. C.; Bozkurt, T. O.; van den Burg, H. A.; Kaschani, F.; Kaiser, M.; Belhaj, K.; Smoker, M.; Joosten, M. H. A. J.; Kamoun, S. et al.; Van der Hoorn, R. A. L.: Functional Divergence of Two Secreted Immune Proteases of Tomato. Current Biology 25 (17), pp. 2300 - 2306 (2015)

MPG.PuRe

DOI

publisher-version

Journal Article

Lu, H.; Chandrasekar, B.; Oeljeklaus, J.; Misas-Villamil, J.; Wang, Z.; Shindo, T.; Bogyo, M.; Kaiser, M.; Van der Hoorn, R. A. L.: Subfamily-Specific Fluorescent Probes for Cysteine Proteases Display Dynamic Protease Activities during Seed Germination. Plant Physiology 168 (4), pp. 1462 - U1636 (2015)

MPG.PuRe

DOI

publisher-version

Journal Article

Ting, H.-M.; Delatte, T. L.; Kolkman, P.; Misas-Villamil, J.; Van der Hoorn, R. A. L.; Bouwmeester, H. J.; van der Krol, A. R.: SNARE-RNAi Results in Higher Terpene Emission from Ectopically Expressed Caryophyllene Synthase in Nicotiana benthamiana. Molecular Plant 8 (3), pp. 454 - 466 (2015)

MPG.PuRe

DOI

publisher-version

2014

Journal Article

Chandrasekar, B.; Colby, T.; Emon, A. E. K.; Jiang, J.; Tram Hong, N.; Villamor, J. G.; Harzen, A.; Overkleeft, H. S.; Van der Hoorn, R. A. L.: Broad-range Glycosidase Activity Profiling. Molelcular & Cellular Proteomics 13 (10), pp. 2787 - 2800 (2014)

MPG.PuRe

DOI

publisher-version

Journal Article

Dong, S.; Stam, R.; Cano, L. M.; Song, J.; Sklenar, J.; Yoshida, K.; Bozkurt, T. O.; Oliva, R.; Liu, Z.; Tian, M. et al.; Win, J.; Banfield, M. J.; Jones, A. M. E.; Van der Hoorn, R. A. L.; Kamoun, S.: Effector Specialization in a Lineage of the Irish Potato Famine Pathogen. SCIENCE 343 (6170), pp. 552 - 555 (2014)

MPG.PuRe

DOI

Journal Article

Sueldo, D.; Ahmed, A.; Misas-Villamil, J.; Colby, T.; Tameling, W.; Joosten, M. H. A. J.; Van der Hoorn, R. A. L.: Dynamic hydrolase activities precede hypersensitive tissue collapse in tomato seedlings. New Phytologist 203 (3), pp. 913 - 925 (2014)

MPG.PuRe

DOI

publisher-version

Journal Article

Zhang, B.; Tremousaygue, D.; Denance, N.; van Esse, H. P.; Hoerger, A. C.; Dabos, P.; Goffner, D.; Thomma, B. P. H. J.; Van der Hoorn, R. A. L.; Tuominen, H.: PIRIN2 stabilizes cysteine protease XCP2 and increases susceptibility to the vascular pathogen Ralstonia solanacearum in Arabidopsis. The Plant Journal 79 (6), pp. 1009 - 1019 (2014)

MPG.PuRe

DOI

publisher-version

2013

Journal Article

Gu, C.; Shannon, D. A.; Colby, T.; Wang, Z.; Shabab, M.; Kumari, S.; Villamor, J. G.; McLaughlin , C. J.; Weerapana , E.; Kaiser, M. et al.; Cravatt, B. F.; Van der Hoorn, R. A. L.: Chemical Proteomics with Sulfonyl Fluoride Probes Reveals Selective Labeling of Functional Tyrosines in Glutathione Transferases. Cell 20 (4), pp. 541 - 548 (2013)

MPG.PuRe

DOI

Journal Article

Hoerger, A. C.; Van der Hoorn, R. A. L.: The structural basis of specific protease-inhibitor interactions at the plant-pathogen interface. Current Opinion in Structural Biology 23 (6), pp. 842 - 850 (2013)

MPG.PuRe

DOI

Journal Article

Ilyas, S.; Ilyas, M.; Van der Hoorn, R. A. L.; Mathur, S.: Selective Conjugation of Proteins by Mining Active Proteomes through Click-Functionalized Magnetic Nanoparticles. ACS NANO 7 (11), pp. 9655 - 9663 (2013)

MPG.PuRe

DOI

Journal Article

Lu, H.; Wang, Z.; Shabab, M.; Oeljeklaus, J.; Verhelst, S. H.; Kaschani, F.; Kaiser, M.; Bogyo, M.; Van der Hoorn, R. A. L.: A substrate-inspired probe monitors translocation, activation, and subcellular targeting of bacterial type III effector protease AvrPphB. Chemistry and Biology 20 (2), pp. 137 - 138 (2013)

MPG.PuRe

DOI

Journal Article

Misas-Villamil, J.; Kolodziejek, I.; Crabill, E.; Kaschani, F.; Niessen, S.; Shindo, T.; Kaiser, M.; Alfano, J. R.; Van der Hoorn, R. A. L.: Pseudomonas syringae pv. syringae Uses Proteasome Inhibitor Syringolin A to Colonize from Wound Infection Sites. PLoS Pathogens 9 (3), e1003281 (2013)

MPG.PuRe

DOI

Full

ZIP

Journal Article

Misas-Villamil, J.; Toenges, G.; Kolodziejek, I.; Sadaghiani, A. M.; Kaschani, F.; Colby, T.; Bogyo, M.; Van der Hoorn, R. A. L.: Activity profiling of vacuolar processing enzymes reveals a role for VPE during oomycete infection. The Plant Journal 73 (4), DOI: 10.1111/tpj.12062, pp. 689 - 700 (2013)

MPG.PuRe

DOI

Journal Article

Nguyen, H. M.; Schippers, J. H. M.; Goni-Ramos, O.; Christoph, M. P.; Dortay, H.; Van der Hoorn, R. L.; Mueller-Roeber, B.: An upstream regulator of the 26S proteasome modulates organ size in Arabidopsis thaliana. The Plant Journal 74 (1), pp. 25 - 36 (2013)

MPG.PuRe

DOI

Journal Article

Villamor, J. G.; Kaschani, F.; Colby, T.; Oeljeklaus, J.; Zhao, D.; Kaiser, M.; Patricelli, M. P.; Van der Hoorn, R. A. L.: Profiling protein kinases and other ATP binding proteins in Arabidopsis using Acyl-ATP probes. Molecular and Cellular Proteomics (12), pp. 2481 - 2496 (2013)

MPG.PuRe

DOI

Journal Article

Zulet, A.; Gil-Monreal, M.; Villamor, J. G.; Zabalza, A.; Van der Hoorn, R. A. L.; Royuela, M.: Proteolytic Pathways Induced by Herbicides That Inhibit Amino Acid Biosynthesis. PLoS One 8 (9), e73847 (2013)

MPG.PuRe

DOI

post-print

2012

Journal Article

Gu, C.; Shabab, M.; Strasser, R.; Wolters, P. J.; Shindo, T.; Niemer, M.; Kaschani, F.; Mach, L.; Van der Hoorn, R. A. L.: Post-Translational Regulation and Trafficking of the Granulin-Containing Protease RD21 of Arabidopsis thaliana. PLoS One 7 (3), e32422 (2012)

MPG.PuRe

DOI

publisher-version

Journal Article

Hoerger, A. C.; Ilyas, M.; Stephan, W.; Tellier, A.; Van der Hoorn, R. A. L.; Rose, L. E.: Balancing Selection at the Tomato RCR3 Guardee Gene Family Maintains Variation in Strength of Pathogen Defense. PLoS Genetics 8 (7), e1002813 (2012)

MPG.PuRe

DOI

publisher-version

Journal Article

Kaschani, F.; Clerc, J.; Krahn, D.; Bier, D.; Hong, T. N.; Ottmann, C.; Niessen, S.; Colby, T.; Van der Hoorn, R. A. L.; Kaiser, M.: Identification of a Selective, Activity-Based Probe for Glyceraldehyde 3-Phosphate Dehydrogenases. Angewandte Chemie-International Edition in English 51 (21), pp. 5230 - 5233 (2012)

MPG.PuRe

DOI

Journal Article

Kaschani, F.; Nickel, S.; Pandey, B.; Cravatt, B. F.; Kaiser, M.; Van der Hoorn, R. A. L.: Selective inhibition of plant serine hydrolases by agrochemicals revealed by competitive ABPP. Bioorganic & Medicinal Chemistry 20 (2), pp. 597 - 600 (2012)

MPG.PuRe

DOI

Journal Article

Lenger, J.; Kaschani, F.; Lenz, T.; Dalhoff, C.; Villamor, J. G.; Villa; Koester, H.; Sewald, N.; Van der Hoorn, R. A. L.: Labeling and enrichment of Arabidopsis thaliana matrix metalloproteases using an active-site directed, marimastat-based photoreactive probe. Bioorganic & Medicinal Chemistry 20 (2), pp. 592 - 596 (2012)

MPG.PuRe

DOI

Journal Article

Lozano-Torres, J. L.; Wilbers, R. H. P.; Gawronski, P.; Boshoven, J. C.; Finkers-Tomczak, A.; Cordewener, J. H. G.; America, A. H. P.; Overmars, H. A.; Van 't Klooster, J. W.; Baranowski, L. et al.; Sobczak, M.; Ilyas, M.; Van der Hoorn, R. A. L.; Schots, A.; de Wit, P. J. G. M.; Bakker, J.; Goverse, A.; Smant, G.: Dual disease resistance mediated by the immune receptor Cf-2 in tomato requires a common virulence target of a fungus and a nematode. Proceedings of the National Academy of Sciences of the United States of America 109 (25), pp. 10119 - 10124 (2012)

MPG.PuRe

DOI

publisher-version

Journal Article

Nickel, S.; Kaschani, F.; Colby, T.; Van der Hoorn, R. A. L.; Kaiser, M.: A para-nitrophenol phosphonate probe labels distinct serine hydrolases of Arabidopsis. Bioorganic & Medicinal Chemistry 20 (2), pp. 601 - 606 (2012)

MPG.PuRe

DOI

Journal Article

Ottmann, C.; Van der Hoorn, R. A. L.; Kaiser, M.: The impact of plant-pathogen studies on medicinal drug discovery. Chemical Society Reviews 41 (8), pp. 3168 - 3178 (2012)

MPG.PuRe

DOI

Journal Article

Richau, K. H.; Kaschani, F.; Verdoes, M.; Pansuriya, T. C.; Niessen, S.; Stueber, K.; Colby, T.; Overkleeft, H. S.; Bogyo, M.; Van der Hoorn, R. A. L.: Subclassification and Biochemical Analysis of Plant Papain-Like Cysteine Proteases Displays Subfamily-Specific Characteristics. Plant Physiology 158 (4), pp. 1583 - 1599 (2012)

MPG.PuRe

DOI

Journal Article

Shannon, D. A.; Gu, C.; McLaughlin, C. J.; Kaiser, M.; Van der Hoorn, R. A. L.; Weerapana, E.: Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases. ChemBioChem: A European Journal of Chemical Biology 13 (16), pp. 2327 - 2330 (2012)

MPG.PuRe

DOI

Journal Article

Shindo, T.; Misas-Villamil, J.; Hoerger, A. C.; Song, J.; Van der Hoorn, R. A. L.: A Role in Immunity for Arabidopsis Cysteine Protease RD21, the Ortholog of the Tomato Immune Protease C14. PLoS One 7 (1), e29317 (2012)

MPG.PuRe

DOI

publisher-version

Journal Article

Stolze, S. C.; Deu, E.; Kaschani, F.; Li, N.; Florea, B.I.; Richau, K. H.; Colby, T.; Van der Hoorn, R. A. L.; Overkleeft, H. S.; Bogyo, M. et al.; Kaiser, M.: The Antimalarial Natural Product Symplostatin 4 Is a Nanomolar Inhibitor of the Food Vacuole Falcipains. Chemistry & Biology 19 (12), pp. 1546 - 1555 (2012)

MPG.PuRe

DOI

Journal Article

Van der Hoorn, R. A. L.; Kaiser, M.: Probes for activity-based profiling of plant proteases. Physiologia Plantarum 145 (1), pp. 18 - 27 (2012)

MPG.PuRe

DOI

Journal Article

van der Linde, K.; Hemetsberger, C.; Kastner, C.; Kaschani, F.; Van der Hoorn, R. A. L.; Kumlehn, J.; Doehlemann, G.: A Maize Cystatin Suppresses Host Immunity by Inhibiting Apoplastic Cysteine Proteases. Plant Cell 24 (3), pp. 1285 - 1300 (2012)

MPG.PuRe

DOI

2011

Journal Article

Bozkurt, T.; Schornack, S.; Win, J.; Shindo, T.; Ilyas, M.; Oliva, R.; Cano, L.; Jones, A. M. E.; Huitema, E.; Van der Hoorn, R. A. L. et al.; Kamoun, S.: Phytophthora infestans effector AVRblb2 prevents secretion of a plant immune protease at the haustorial interface. Proceedings of the National Academy of Sciences of the United States of America 108 (51), pp. 20832 - 20837 (2011)

MPG.PuRe

DOI

Journal Article

Kaschani, F.; Van der Hoorn, R. A. L.: A model of the C14-EPIC complex indicates hotspots for a protease-inhibitor arms race in the oomycete-potato interaction. Plant signaling & behavior 6, pp. 1 - 4 (2011)

MPG.PuRe

Journal Article

Kolodziejek, I.; Misas-Villamil, J.; Kaschani, F.; Clerc, J.; Gu, C.; Krahn, D.; Niessen, S.; Verdoes, M.; Willems, L.I.; Overkleeft, H. S. et al.; Kaiser, M.; Van der Hoorn, R. A. L.: Proteasome Activity Imaging and Profiling Characterizes Bacterial Effector Syringolin A. Plant Physiology 155 (1), 10.1104/pp.110.163733, pp. 477 - 489 (2011)

MPG.PuRe

DOI

Journal Article

Lenz, H. D.; Haller, E.; Melzer, E.; Kober, K.; Wurster, K.; Stahl, M.; Bassham, D. C.; Vierstra, R. D.; Parker, J. E.; Bautor, J. et al.; Molina, A.; Escudero, V.; Shindo, T.; van der Hoorn, R. A. L.; Gust, A. A.; Nurnberger, T.: Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens. Plant Journal 66 (5), pp. 818 - 830 (2011)

MPG.PuRe

Journal Article

Misas-Villamil, J.; Kolodziejek, I.; Van der Hoorn, R. L.: Pseudomonas syringae colonizes distant tissues in Nicotiana benthamiana through xylem vessels. PLANT JOURNAL 67 (5), pp. 774 - 782 (2011)

MPG.PuRe

DOI

Journal Article

Ramasubramanian, S. K.; Van der Hoorn, R. A. L.: A structural biology perspective on bioactive small molecules and their plant targets. Current Opinion in Plant Biology 14 (5), pp. 480 - 488 (2011)

MPG.PuRe

DOI

Journal Article

Richau, K. H.; Van der Hoorn, R. A. L.: Studies on plant-pathogen interactions using activity-based proteomics. Current Proteomics 7, pp. 328 - 336 (2011)

MPG.PuRe

Journal Article

Van der Hoorn, R. A. L.; Colby, T.; Nickel, S.; Richau, K. H.; Schmidt, J.; Kaiser, M.: Mining the active proteome of Arabidopsis thaliana. Frontiers in Plant Science 2, 10.3389/fpls.2011.00089, p. 89 (2011)

MPG.PuRe

DOI

2010

Journal Article

Gu, C.; Kolodziejek, I.; Misas-Villamil, J.; Shindo, T.; Colby, T.; Verdoes, M.; Richau, K. H.; Schmidt, J.; Overkleeft, H. S.; Van der Hoorn, R. A. L.: Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities. Plant Journal 62, 10.1111/j.1365-313X.2009.04122.x, pp. 160 - 170 (2010)

MPG.PuRe

Publications of R. A. L. Van der Hoorn

Journal Article (67)