The organization of DNA with histone proteins into chromatin is fundamental to the regulation of gene expression. Incorporation of different histone variants into the nucleosome, together with post-translational modifications of these histone variants, allows modulation of chromatin accessibility and contributes to the regulation of gene expression necessary for the organism to respond to developmental and environmental cues. We are interested in the changes in chromatin organization and gene expression that occur during developmental transitions. I will discuss our recent data investigating the concerted changes in the transcriptome, histone variant repertoire, and nuclear organization during the seed-to-seedling transition.
